Before the Chuunin Exams - Childhood/genin
Ino was brought into Naruto through Sakura, being her child hood friend who pulled her out of her depression, due to constant bullying of her oversized forehead. She befriended her and the two were considered best friends until Sakura found out that Ino liked Sasuke, just like Sakura. Sakura ended the friendship instantly. The two grew apart until the chuunin exams in which this game is set, in which they versed each other and rekindled their friendship.
Chūnin Exam arc
Though making a few brief appearances earlier in the series, Ino made her debut during the Chūnin Exams. She used her Mind Body Switch Technique to enter Sakura's mind and memorize all her test answers, then sent her mind into Chōji and Shikamaru's minds to give them the answers. In the Forest of Death, Ino had many flashbacks of her childhood when they saw Sakura was in danger, she and her team helped Sakura and Rock Lee fight off the Sound Genin, until Sasuke forced the Sound Genin to retreat.
Ino fighting Sakura during her preliminary match.
Ino's first match in the Chūnin Exams was against Sakura. The two did not battle seriously at first, until Sakura, unwilling to have Ino pity her, denounced her. Ino and Sakura battled seriously afterwards, and used up most of their energy in the process. Ino then attempted to enter Sakura's mind after cutting her hair and sending chakra into it to immobilize her. She succeeded, but was expelled by Inner Sakura. Low on chakra, Ino and Sakura charged at each other for one last attack, and knocked each other out, resulting in both of them being eliminated. When they regained consciousness, they started becoming friends again, but still maintained their rivalry over Sasuke.
Ino accompanied Sakura to visit Sasuke in the month between the preliminaries and the finals, but found that he was gone. She went to the finals with Sakura, and noted that Sakura's team was extraordinary, after seeing Naruto defeat Neji. When the invasion started, she was rendered unconscious by Kabuto's genjutsu.
Anime filler arcs
In the filler arcs, Ino accompanied Naruto, Shino and Anko to the Land of the Sea, and helped defeat Misumi Tsurugi, by possessing him and tying his arms to pillars, leaving him trapped in a collapsing room. Ino then used Mind Body Disturbance Technique on Yoroi as he attempted to attack Shino, allowing Shino to punch Yoroi away. When Yoroi attempted to attack Ino, Shino sent his bugs after him, thus defeating him.
She later appeared in a mission with Naruto, in which she tried to replace a princess who had grown overweight in an attempt to woo her suitor. Ino was barely able to stand the man, but the mission succeeded, after Naruto accidentally exposed the real princess. Ino briefly revealed an "Inner Ino", similar to Sakura's "Inner Sakura", during this episode.
In the Konoha 11 arc, Ino and Sakura were sent to examine a corpse that was believed to be that of Gennō. Ino hesitated, but eventually entered the room, and concluded, from the condition of the hands, that the corpse was not a ninja or a carpenter, and that Gennō was still alive. After the group found Gennō, she attempted to possess him when he tried to make his escape on a summoned bird; while he let go of the bird, Ino was unable to maintain the technique, as she noted that he had been suffering terrible pain the entire time.
In Episode 158; Follow My Lead! The Great Survival Challenge, the Academy Students were divided into teams of three and were assigned to a genin who would lead them on a mission against the other teams. Ino was assigned to lead a team of three academy students; Sou, Kiri and, Shimo. Her time with them was not covered much except that she was doing better than Naruto.
In the Shitenshounin arc
Ino accompanied Shikamaru to help rescue Temari. Her attempt at possessing their opponent, Kujaku, failed, leaving her at risk. Kujaku later was defeated by Shikamaru and Temari's combined efforts. Feeling guilty that she did not contribute much to the mission, she asked Sakura to ask Tsunade to add her as a second apprentice. Sakura agreed, but added that she would be Ino's senior apprentice, resulting in Ino refusing (which led to yet another fight).
Sasuke and Sai arc
Ino made her first reappearance shortly after Team Kakashi and Team Guy returned from the successful saving of Gaara. She appeared again after Naruto and his team returned from their failed attempt to retrieve Sasuke. Upon meeting Sai, she quickly became interested in him, also noting that he resembled Sasuke. When they all went out to dinner, Ino attempted to get Sai's attention with some subtle flirting. When Sai tried to befriend Ino and Chōji, having earlier come to the conclusion that women (specifically Sakura), didn't like to hear how they really looked, Sai tried the opposite approach by calling Ino "gorgeous", of which is the opposite of what he wanted to say. This resulted in Ino blushing, and enraging Sakura, who Sai had previously called "ugly".
Twelve Guardian Ninja arc
In the anime, Ino made her next appearance while selling flowers to Asuma at her family's shop, teasing Asuma about his gift obviously being for Kurenai. When word came that villages on the border of the Land of Fire were being attacked, Ino, along with the rest of Team Asuma and some ninjas went to investigate. Later, during the attack on Konoha, where a horde of ninja zombies appeared, Ino did her part in the resistance by performing her duties as a medical ninja. After the jutsu that brought the zombies were dispelled, Ino together with her team mates went to the location where Sora was manifesting the Nine Tails's powers. After Chōji's defeat, Shikamaru ordered Ino to take over Sora's mind and stop him. As she entered Sora's mind, she was threatened by the Pseudo-Nine Tails within him and she was told that Sora was already consumed by the monster. Ino's failure then brought her back to her own body. The Nine Tails then attacked them but Yamato was able to shield them. Ino then tried to heal Chōji's hands but she failed since wounds caused by the Nine Tail's chakra could not have easily been healed even by medical jutsu.
Hidan and Kakuzu arc
When Tsunade decided to make a move against Akatsuki, Ino was assigned, along with Chōji, to a Nijū Shōtai team, led by Raido Namiashi and Aoba Yamashiro. Ino and Chōji arrived as back-up for Shikamaru and Asuma in their fight with Akatsuki members Hidan and Kakuzu. When the duo retreated, Ino tried to tend to Asuma's injuries, but the damage to his body was beyond repair. The team then had nothing to do but listen to Asuma's last words. Before dying, Asuma said that Ino is strong-willed and a reliable child, so she should take care of Chōji and Shikamaru. Asuma also told Ino not to lose to Sakura in ninjutsu or in love, to which Ino agreed. Ino then reminisces about her memories with Asuma especially her first days with him as a student, and when she noticed that the bouquet of flowers that Asuma bought were for Kurenai. After the death of her sensei, Ino screamed out loud with grief.
Shikamaru, Ino, and Chōji all agreed to avenge Asuma. Under the guidance of Kakashi, Team 10 later set out to face Kakuzu and Hidan. By using her Mind Body Switch Technique on a hawk, Ino was able to quickly find the Akatsuki duo so Shikamaru's plan could begin. During Team 10's fight with Hidan and Kakuzu, Ino largely played the role of an observer, her Mind Body Switch Technique being too much of a risk to use in battle. After Naruto arrived and defeated Kakuzu, she happily healed him.
Three-Tailed Beast arc
In the anime, keeping true to her promise, Ino was seen taking part in a serious operation, and was praised for her efforts by a more experienced Medical-ninja. Ino was later teamed with Rock Lee and Tenten as back-up for Kakashi's team. Her mission would be using her fine-tuned chakra control to assist in the sealing of the recently discovered Three-Tailed Beast.
After arriving, and having another argument with Sakura, she was put under Shizune's command to directly help seal the beast. While initially having some difficulty handling the technique, her refusal to be outdone by Sakura pushed her to keep her composure.
Unfortunately, the enemies were able to break the seal. Upon the Three-Tails' emergence, Ino was knocked unconscious and rescued by Lee. After recovering, Ino admitted to how useless she felt, swearing to make up for it. She then joined Sakura in healing the young boy, Yukimaru, that was being used by Orochimaru's men.
After learning that Naruto was trapped in the belly of the Three-Tails, Ino joined the team in another attempt to save Naruto and seal the Three-Tails. The attempt ended in failure, and Ino was knocked out again.
Invasion of Pain arc
When Pain began his invasion, Ino rushed to her father's location to inform him and all those present of the attack. Having learned something about Pain's identity, they tried to escape, to avoid capture. Despite their attempt, Pain arrived and captured Shizune, finding out what she knew, before killing her. After he destroyed the village, Ino tried to revive Shizune, but could do nothing to help her, and regrouped with her father and the others. After the death of Nagato, she was shocked to see that Shizune was brought back to life. She was then present at Naruto's return, and celebrated with the villagers for his victory.
Five Kage Summit arc
Ino is first seen crying when she finds out that Sasuke has been raised to the status of international criminal. When Kiba demands she stop crying, she is defended by Tenten. After this, she is among the few that Shikamaru noted would never forgive Kumogakure if they had some hand in Sasuke's death, alongside Naruto and Sakura. Later, it was revealed to Naruto by Sai that Konoha 11 was planning to kill Sasuke. Ino was supposedly part of this, since all of Konoha 11, besides Naruto were involved in the plot.
Custom Arch
Ino was suppose to be heading out soon after she stop to have lunch with her old team mates at the ramen stand. She was not wanting to do this to Sauske, she love him too much but she was sadden by the fact he was letting this happen to himself. She was determented to stop him and get him to realized what he was doing. But before anything could happen they found her pass out a shortly 30 minutes later. She fall into a deep coma, one they fear she would not return in. So she was lock into a room where she could rest in peace, if she ever came back.
Ino end up founding herself in a strange new world, surrounded by snow. She was continue, cold and lost. She wonder how she could end up here. Was her team mates around anywhere, and what was her purpose in this world. She was determined to find out what this world was about and maybe find some relation of her clan here.